IL37 (NM_014439) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp) . This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
FIL1; FIL1 (ZETA) ; FIL1Z; IL-1F7; IL-1H; IL-1H4; IL-1RP1; IL-23; IL-37; IL1F7; IL1H4; IL1RP1
Gene ID
27178
UniProt
Q9NZH6
Accession Number mRNA
NM_014439
Chromosomal Location
2q14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
23.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IL37
Species
Human
Protein ID
NP_055254
Overview
Recombinant protein of human interleukin 1 family, member 7 (zeta) (IL1F7), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27178
Uniprot URL
https://www.uniprot.org/uniprot/Q9NZH6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014439
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055254
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