DENND10 (NM_207009) Human Recombinant Protein
Product Specifications
Background
Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.[UniProtKB/Swiss-Prot Function]
Synonyms
FAM45A
Gene ID
404636
UniProt
Q8TCE6
Accession Number mRNA
NM_207009
Chromosomal Location
10q26.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
40.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DENND10
Species
Human
Protein ID
NP_996892
Overview
Recombinant protein of human family with sequence similarity 45, member A (FAM45A)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/404636
Uniprot URL
https://www.uniprot.org/uniprot/Q8TCE6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_207009
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_996892
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