VPREB3 (NM_013378) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR) . While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]
Synonyms
8HS20; N27C7-2
Gene ID
29802
UniProt
Q9UKI3
Accession Number mRNA
NM_013378
Chromosomal Location
22q11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
13.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VPREB3
Species
Human
Protein ID
NP_037510
Overview
Recombinant protein of human pre-B lymphocyte 3 (VPREB3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29802
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKI3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013378
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037510
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