Neuroligin 4 (NLGN4X) (NM_181332) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4) . Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Overview
Recombinant protein of human neuroligin 4, X-linked (NLGN4X), transcript variant 2
Synonyms
ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4
Gene ID
57502
UniProt
Q8N0W4, A0A024RBV0
Accession Number mRNA
NM_181332
Chromosomal Location
Xp22.32-p22.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell adhesion molecules (CAMs)
Field of Research
Cell adhesion molecules (CAMs)
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
91.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NLGN4X
Species
Human
Protein ID
NP_851849
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57502
Uniprot URL
https://www.uniprot.org/uniprot/Q8N0W4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_181332
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_851849
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