DARC (ACKR1) (NM_002036) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CCBP1; CD234; DARC; DARC/ACKR1; Dfy; FY; GPD; GpFy; WBCQ1
Gene ID
2532
UniProt
Q16570, Q5Y7A2
Accession Number mRNA
NM_002036
Chromosomal Location
1q23.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, GPCR, Transmembrane
Molecular Weight
35.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACKR1
Species
Human
Protein ID
NP_002027
Overview
Recombinant protein of human Duffy blood group, chemokine receptor (DARC), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2532
Uniprot URL
https://www.uniprot.org/uniprot/Q16570
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002036
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002027
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
