MD2 (LY96) (NM_015364) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]
Synonyms
ESOP-1; ly-96; MD-2; MD2
Gene ID
23643
UniProt
Q9Y6Y9
Accession Number mRNA
NM_015364
Chromosomal Location
8q21.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
Field of Research
Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
25605324
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
18.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LY96
Species
Human
Protein ID
NP_056179
Overview
Recombinant protein of human lymphocyte antigen 96 (LY96)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23643
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y6Y9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015364
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056179
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