MD2 (LY96) (NM_015364) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]

Overview

Recombinant protein of human lymphocyte antigen 96 (LY96)

Synonyms

ESOP-1; ly-96; MD-2; MD2

Gene ID

23643

UniProt

Q9Y6Y9

Accession Number mRNA

NM_015364

Chromosomal Location

8q21.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway

Field of Research

Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

25605324

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

18.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.