CLIC2 (NM_001289) Human Recombinant Protein
Selected Variant
PH39681M5
Size: 20 µg
Product Specifications
Background
This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]
Overview
Recombinant protein of human chloride intracellular channel 2 (CLIC2)
Synonyms
CLCNL2; CLIC2b; MRXS32; XAP121
Gene ID
1193
UniProt
O15247
Accession Number mRNA
NM_001289
Chromosomal Location
Xq28
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
28862243
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Ion Channels: Other
Molecular Weight
28.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CLIC2
Species
Human
Protein ID
NP_001280
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1193
Uniprot URL
https://www.uniprot.org/uniprot/O15247
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001289
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001280
Price
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