C4BPA (NM_000715) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human complement component 4 binding protein, alpha (C4BPA)
Synonyms
C4BP; PRP
Gene ID
722
UniProt
P04003
Accession Number mRNA
NM_000715
Chromosomal Location
1q32.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Complement and coagulation cascades
Field of Research
Complement and coagulation cascades
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
61.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C4BPA
Species
Human
Protein ID
NP_000706
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/722
Uniprot URL
https://www.uniprot.org/uniprot/P04003
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000715
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000706
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