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RPB11 (POLR2J) (NM_006234) Human Recombinant Protein

Product Specifications

Background

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa (POLR2J)

Synonyms

HRPB14; POLR2J1; RPB11; RPB11A; RPB11m

Gene ID

5439

UniProt

P52435

Accession Number mRNA

NM_006234

Chromosomal Location

7q22.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Field of Research

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

13.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

POLR2J

Species

Human

Protein ID

NP_006225

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5439

Uniprot URL

https://www.uniprot.org/uniprot/P52435

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006234

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006225

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