COG2 (NM_007357) Human Recombinant Protein
Product Specifications
Background
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]
Overview
Recombinant protein of human component of oligomeric golgi complex 2 (COG2), transcript variant 1
Synonyms
CDG2Q; LDLC
Gene ID
22796
UniProt
Q14746, B1ALW7
Accession Number mRNA
NM_007357
Chromosomal Location
1q42.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
83 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
COG2
Species
Human
Protein ID
NP_031383
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22796
Uniprot URL
https://www.uniprot.org/uniprot/Q14746
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007357
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031383
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