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MTF1 (NM_005955) Human Recombinant Protein

Selected Variant

PH39617M5

Size: 20 µg

Product Specifications

Background

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE) . [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human metal-regulatory transcription factor 1 (MTF1)

Synonyms

MTF-1; ZRF

Gene ID

4520

UniProt

Q14872

Accession Number mRNA

NM_005955

Chromosomal Location

1p34.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

80.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MTF1

Species

Human

Protein ID

NP_005946

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4520

Uniprot URL

https://www.uniprot.org/uniprot/Q14872

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005955

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005946

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