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Munc18 1 (STXBP1) (NM_001032221) Human Recombinant Protein

Product Specifications

Background

This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

Overview

Recombinant protein of human syntaxin binding protein 1 (STXBP1), transcript variant 2

Synonyms

DEE4; MUNC18-1; N-Sec1; NSEC1; P67; RBSEC1; unc-18A; UNC18; unc18-1

Gene ID

6812

UniProt

P61764

Accession Number mRNA

NM_001032221

Chromosomal Location

9q34.11

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

67.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

STXBP1

Species

Human

Protein ID

NP_001027392

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6812

Uniprot URL

https://www.uniprot.org/uniprot/P61764

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001032221

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001027392

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