PSMD5 (NM_005047) Human Recombinant Protein
Product Specifications
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly. [provided by RefSeq, Jul 2012]
Synonyms
S5B
Gene ID
5711
UniProt
Q16401
Accession Number mRNA
NM_005047
Chromosomal Location
9q33.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
56 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PSMD5
Species
Human
Protein ID
NP_005038
Overview
Recombinant protein of human proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 (PSMD5)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5711
Uniprot URL
https://www.uniprot.org/uniprot/Q16401
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005047
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005038
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