TBC1D20 (NM_144628) Human Recombinant Protein
Selected Variant
PH39584M5
Size: 20 µg
Product Specifications
Background
This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Overview
Recombinant protein of human TBC1 domain family, member 20 (TBC1D20)
Synonyms
C20orf140; WARBM4
Gene ID
128637
UniProt
Q96BZ9, Q9Y2V8
Accession Number mRNA
NM_144628
Chromosomal Location
20p13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
45.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TBC1D20
Species
Human
Protein ID
NP_653229
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/128637
Uniprot URL
https://www.uniprot.org/uniprot/Q96BZ9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144628
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_653229
Price
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