Serum amyloid A2 (SAA2) (NM_030754) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. [provided by RefSeq, Jul 2020]
Synonyms
Serum amyloid A2
Gene ID
6289
UniProt
P02735, P0DJI9
Accession Number mRNA
NM_030754
Chromosomal Location
11p15.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
29757436
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
13.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SAA2
Species
Human
Protein ID
NP_110381
Overview
Recombinant protein of human serum amyloid A2 (SAA2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6289
Uniprot URL
https://www.uniprot.org/uniprot/P02735
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030754
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_110381
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