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Serum amyloid A2 (SAA2) (NM_030754) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. [provided by RefSeq, Jul 2020]

Overview

Recombinant protein of human serum amyloid A2 (SAA2), transcript variant 1

Synonyms

Serum amyloid A2

Gene ID

6289

UniProt

P02735, P0DJI9

Accession Number mRNA

NM_030754

Chromosomal Location

11p15.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

29757436

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

13.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SAA2

Species

Human

Protein ID

NP_110381

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6289

Uniprot URL

https://www.uniprot.org/uniprot/P02735

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_030754

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_110381

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