UBE2W (NM_018299) Human Recombinant Protein
Product Specifications
Background
This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
UBC-16; UBC16
Gene ID
55284
UniProt
Q96B02
Accession Number mRNA
NM_018299
Chromosomal Location
8q21.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
17.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2W
Species
Human
Protein ID
NP_060769
Overview
Recombinant protein of human ubiquitin-conjugating enzyme E2W (putative) (UBE2W), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55284
Uniprot URL
https://www.uniprot.org/uniprot/Q96B02
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018299
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060769
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