PC4 (SUB1) (NM_006713) Human Recombinant Protein

Product Specifications

Background

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human SUB1 homolog (S. cerevisiae) (SUB1)

Synonyms

P14; P15; PC4

Gene ID

10923

UniProt

P53999, Q6IBA2

Accession Number mRNA

NM_006713

Chromosomal Location

5p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

14.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.