TWIST2 (NM_057179) Human Recombinant Protein
Selected Variant
PH39545M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014]
Overview
Recombinant protein of human twist homolog 2 (Drosophila) (TWIST2)
Synonyms
AMS; BBRSAY; bHLHa39; DERMO1; FFDD3; SETLSS
Gene ID
117581
UniProt
Q8WVJ9, A1MB48
Accession Number mRNA
NM_057179
Chromosomal Location
2q37.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
17.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TWIST2
Species
Human
Protein ID
NP_476527
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/117581
Uniprot URL
https://www.uniprot.org/uniprot/Q8WVJ9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_057179
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_476527
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