UPRT (NM_145052) Human Recombinant Protein
Product Specifications
Background
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP) . This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]
Synonyms
FUR1; UPP
Gene ID
139596
UniProt
Q96BW1, A8KAF9
Accession Number mRNA
NM_145052
Chromosomal Location
Xq13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Pyrimidine metabolism
Field of Research
Metabolic pathways, Pyrimidine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
33.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UPRT
Species
Human
Protein ID
NP_659489
Overview
Recombinant protein of human uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) (UPRT)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/139596
Uniprot URL
https://www.uniprot.org/uniprot/Q96BW1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145052
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_659489
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