PPP1R1C (NM_001080545) Human Recombinant Protein

Product Specifications

Background

Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]) .[supplied by OMIM, Feb 2010]

Overview

Recombinant protein of human protein phosphatase 1, regulatory (inhibitor) subunit 1C (PPP1R1C)

Synonyms

IPP5

Gene ID

151242

UniProt

Q8WVI7

Accession Number mRNA

NM_001080545

Chromosomal Location

2q31.3-q32.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Phosphatase

Molecular Weight

12.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.