SH2D1B (NM_053282) Human Recombinant Protein
Product Specifications
Background
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]) .[supplied by OMIM, Mar 2008]
Overview
Recombinant protein of human SH2 domain containing 1B (SH2D1B)
Synonyms
EAT2
Gene ID
117157
UniProt
O14796
Accession Number mRNA
NM_053282
Chromosomal Location
1q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Natural killer cell mediated cytotoxicity
Field of Research
Natural killer cell mediated cytotoxicity
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
15.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SH2D1B
Species
Human
Protein ID
NP_444512
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/117157
Uniprot URL
https://www.uniprot.org/uniprot/O14796
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_053282
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_444512
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