Annexin A2 (ANXA2) (NM_001002857) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019]
Synonyms
ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV
Gene ID
302
UniProt
P07355, A0A024R5Z7
Accession Number mRNA
NM_001002857
Chromosomal Location
15q22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Stem cell - Pluripotency
Molecular Weight
38.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ANXA2
Species
Human
Protein ID
NP_001002857
Overview
Recombinant protein of human annexin A2 (ANXA2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/302
Uniprot URL
https://www.uniprot.org/uniprot/P07355
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001002857
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001002857
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