AASDHPPT (NM_015423) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT)

Synonyms

AASD-PPT; ACPS; CGI-80; LYS2; LYS5

Gene ID

60496

UniProt

Q9NRN7

Accession Number mRNA

NM_015423

Chromosomal Location

11q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Lysine biosynthesis, Lysine degradation, Metabolic pathways

Field of Research

Lysine biosynthesis, Lysine degradation, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

35.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.