SOX8 (NM_014587) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the cognitive disability found in an alpha-thalassemia-related syndrome (ART-16) . This protein is also highly expressed in the majority of human hepatocellular carcinomas and promotes cellular proliferation and enhanced tumor growth. [provided by RefSeq, Jul 2017]
Synonyms
MGC24837
Gene ID
30812
UniProt
P57073
Accession Number mRNA
NM_014587
Chromosomal Location
16p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
47.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SOX8
Species
Human
Protein ID
NP_055402
Overview
Recombinant protein of human SRY (sex determining region Y) -box 8 (SOX8)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/30812
Uniprot URL
https://www.uniprot.org/uniprot/P57073
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014587
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055402
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