CPLX3 (NM_001030005) Human Recombinant Protein

Product Specifications

Background

Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity) . Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity) . Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity) . Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca (2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca (2+) vesicle release (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human complexin 3 (CPLX3)

Synonyms

CPX-III; CPXIII; Nbla11589

Gene ID

594855

UniProt

Q8WVH0, A0A384N6F4

Accession Number mRNA

NM_001030005

Chromosomal Location

15q24.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

17.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.