CPLX3 (NM_001030005) Human Recombinant Protein
Product Specifications
Background
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity) . Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity) . Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity) . Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca (2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca (2+) vesicle release (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
CPX-III; CPXIII; Nbla11589
Gene ID
594855
UniProt
Q8WVH0, A0A384N6F4
Accession Number mRNA
NM_001030005
Chromosomal Location
15q24.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
17.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CPLX3
Species
Human
Protein ID
NP_001025176
Overview
Recombinant protein of human complexin 3 (CPLX3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/594855
Uniprot URL
https://www.uniprot.org/uniprot/Q8WVH0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001030005
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001025176
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