OGDHL (NM_018245) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016]
Overview
Recombinant protein of human oxoglutarate dehydrogenase-like (OGDHL), transcript variant 1
Synonyms
FLJ10851
Gene ID
55753
UniProt
Q9ULD0
Accession Number mRNA
NM_018245
Chromosomal Location
10q11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism
Field of Research
Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
114.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
OGDHL
Species
Human
Protein ID
NP_060715
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55753
Uniprot URL
https://www.uniprot.org/uniprot/Q9ULD0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018245
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060715
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