CRHBP (NM_001882) Human Recombinant Protein
Product Specifications
Background
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human corticotropin releasing hormone binding protein (CRHBP)
Synonyms
CRF-BP; CRFBP
Gene ID
1393
UniProt
P24387
Accession Number mRNA
NM_001882
Chromosomal Location
5q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
36 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CRHBP
Species
Human
Protein ID
NP_001873
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1393
Uniprot URL
https://www.uniprot.org/uniprot/P24387
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001882
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001873
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