G protein alpha inhibitor 1 (GNAI1) (NM_002069) Human Recombinant Protein
Selected Variant
PH39418M5
Size: 20 µg
Product Specifications
Background
Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Overview
Recombinant protein of human guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1)
Synonyms
Gi
Gene ID
2770
UniProt
P63096
Accession Number mRNA
NM_002069
Chromosomal Location
7q21.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction
Field of Research
Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
40.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GNAI1
Species
Human
Protein ID
NP_002060
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2770
Uniprot URL
https://www.uniprot.org/uniprot/P63096
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002069
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002060
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