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G protein alpha inhibitor 1 (GNAI1) (NM_002069) Human Recombinant Protein

Selected Variant

PH39418M5

Size: 20 µg

Product Specifications

Background

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Overview

Recombinant protein of human guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1)

Synonyms

Gi

Gene ID

2770

UniProt

P63096

Accession Number mRNA

NM_002069

Chromosomal Location

7q21.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction

Field of Research

Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

40.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GNAI1

Species

Human

Protein ID

NP_002060

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2770

Uniprot URL

https://www.uniprot.org/uniprot/P63096

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002069

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002060

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