What is the catalog number for PDE1A (NM_005019) Human Recombinant Protein?

The catalog number for PDE1A (NM_005019) Human Recombinant Protein is PH39417M5.

What sizes are available for PDE1A (NM_005019) Human Recombinant Protein?

PDE1A (NM_005019) Human Recombinant Protein is available in the following size(s): 20 µg.

Is PDE1A (NM_005019) Human Recombinant Protein in stock?

PDE1A (NM_005019) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

PDE1A (NM_005019) Human Recombinant Protein

Product Specifications

Background

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) .[supplied by OMIM, Oct 2009]

Overview

Recombinant protein of human phosphodiesterase 1A, calmodulin-dependent (PDE1A), transcript variant 1

Synonyms

CAM-PDE-1A; CAM-PDE 1A; HCAM-1; HCAM1; HSPDE1A

Gene ID

5136

UniProt

P54750

Accession Number mRNA

NM_005019

Chromosomal Location

2q32.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction

Field of Research

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

62.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.