EPS8 (NM_004447) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Synonyms
DFNB102
Gene ID
2059
UniProt
Q12929, B4E3T6
Accession Number mRNA
NM_004447
Chromosomal Location
12p12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
91.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EPS8
Species
Human
Protein ID
NP_004438
Overview
Recombinant protein of human epidermal growth factor receptor pathway substrate 8 (EPS8)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2059
Uniprot URL
https://www.uniprot.org/uniprot/Q12929
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004447
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004438
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