DGKZ (NM_003646) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

Overview

Recombinant protein of human diacylglycerol kinase, zeta 104kDa (DGKZ), transcript variant 2

Synonyms

DAGK5; DAGK6; DGK-ZETA; hDGKzeta

Gene ID

8525

UniProt

Q13574

Accession Number mRNA

NM_003646

Chromosomal Location

11p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Field of Research

Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

103.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DGKZ

Species

Human

Protein ID

NP_003637

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8525

Uniprot URL

https://www.uniprot.org/uniprot/Q13574

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003646

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003637

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