DDI1 (NM_001001711) Human Recombinant Protein
Product Specifications
Background
Probable aspartic protease (Probable) . Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable) . Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (PubMed:29290612) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae) (DDI1)
Synonyms
FLJ36017
Gene ID
414301
UniProt
Q8WTU0
Accession Number mRNA
NM_001001711
Chromosomal Location
11q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
43.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DDI1
Species
Human
Protein ID
NP_001001711
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/414301
Uniprot URL
https://www.uniprot.org/uniprot/Q8WTU0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001001711
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001001711
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