DDI1 (NM_001001711) Human Recombinant Protein

Product Specifications

Background

Probable aspartic protease (Probable) . Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable) . Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (PubMed:29290612) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae) (DDI1)

Synonyms

FLJ36017

Gene ID

414301

UniProt

Q8WTU0

Accession Number mRNA

NM_001001711

Chromosomal Location

11q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

43.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.