DPP10 (NM_020868) Human Recombinant Protein
Product Specifications
Background
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human dipeptidyl-peptidase 10 (DPP10), transcript variant 1
Synonyms
DPL2; DPPY; DPRP-3; DPRP3
Gene ID
57628
UniProt
Q8N608, B2RCJ8
Accession Number mRNA
NM_020868
Chromosomal Location
2q14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease, Transmembrane
Molecular Weight
90.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DPP10
Species
Human
Protein ID
NP_065919
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57628
Uniprot URL
https://www.uniprot.org/uniprot/Q8N608
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020868
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065919
Frequently Asked Questions
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