HACE1 (NM_020771) Human Recombinant Protein
Product Specifications
Background
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]
Synonyms
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1; SPPRS
Gene ID
57531
UniProt
Q8IYU2
Accession Number mRNA
NM_020771
Chromosomal Location
6q16.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
102.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HACE1
Species
Human
Protein ID
NP_065822
Overview
Recombinant protein of human HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (HACE1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57531
Uniprot URL
https://www.uniprot.org/uniprot/Q8IYU2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020771
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065822
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