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ASRGL1 (NM_025080) Human Recombinant Protein

Product Specifications

Background

Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human asparaginase like 1 (ASRGL1), transcript variant 2

Synonyms

ALP; ALP1; CRASH

Gene ID

80150

UniProt

Q7L266, A0A024R573

Accession Number mRNA

NM_025080

Chromosomal Location

11q12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Protease

Molecular Weight

31.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ASRGL1

Species

Human

Protein ID

NP_079356

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/80150

Uniprot URL

https://www.uniprot.org/uniprot/Q7L266

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_025080

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_079356

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