SIRT7 (NM_016538) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
Synonyms
SIR2L7
Gene ID
51547
UniProt
Q9NRC8
Accession Number mRNA
NM_016538
Chromosomal Location
17q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
28147277
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
44.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SIRT7
Species
Human
Protein ID
NP_057622
Overview
Recombinant protein of human sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51547
Uniprot URL
https://www.uniprot.org/uniprot/Q9NRC8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016538
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057622
Curated Selection
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