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Moesin (MSN) (NM_002444) Human Recombinant Protein

Product Specifications

Background

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]

Synonyms

HEL70; IMD50

Gene ID

4478

UniProt

P26038, V9HWC0

Accession Number mRNA

NM_002444

Chromosomal Location

Xq12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Leukocyte transendothelial migration, Regulation of actin cytoskeleton

Field of Research

Leukocyte transendothelial migration, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

67.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MSN

Species

Human

Protein ID

NP_002435

Overview

Recombinant protein of human moesin (MSN)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4478

Uniprot URL

https://www.uniprot.org/uniprot/P26038

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002444

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002435

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