Moesin (MSN) (NM_002444) Human Recombinant Protein
Product Specifications
Background
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human moesin (MSN)
Synonyms
HEL70; IMD50
Gene ID
4478
UniProt
P26038, V9HWC0
Accession Number mRNA
NM_002444
Chromosomal Location
Xq12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Leukocyte transendothelial migration, Regulation of actin cytoskeleton
Field of Research
Leukocyte transendothelial migration, Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
67.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MSN
Species
Human
Protein ID
NP_002435
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4478
Uniprot URL
https://www.uniprot.org/uniprot/P26038
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002444
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002435
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