ZNF259 (ZPR1) (NM_003904) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Synonyms
GKAF; ZNF259
Gene ID
8882
UniProt
O75312
Accession Number mRNA
NM_003904
Chromosomal Location
11q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
50.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ZPR1
Species
Human
Protein ID
NP_003895
Overview
Recombinant protein of human zinc finger protein 259 (ZNF259)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8882
Uniprot URL
https://www.uniprot.org/uniprot/O75312
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003904
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003895
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