DEK (NM_003472) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Overview
Recombinant protein of human DEK oncogene (DEK), transcript variant 1
Synonyms
D6S231E
Gene ID
7913
UniProt
P35659
Accession Number mRNA
NM_003472
Chromosomal Location
6p22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
42.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DEK
Species
Human
Protein ID
NP_003463
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7913
Uniprot URL
https://www.uniprot.org/uniprot/P35659
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003472
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003463
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