FTSJD2 (CMTR1) (NM_015050) Human Recombinant Protein
Product Specifications
Background
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m (7) GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m (7) GpppRm (cap1) . Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.[UniProtKB/Swiss-Prot Function]
Synonyms
FTSJD2; hMTr1; KIAA0082; MTr1
Gene ID
23070
UniProt
Q8N1G2
Accession Number mRNA
NM_015050
Chromosomal Location
6p21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
95.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CMTR1
Species
Human
Protein ID
NP_055865
Overview
Recombinant protein of human FtsJ methyltransferase domain containing 2 (FTSJD2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23070
Uniprot URL
https://www.uniprot.org/uniprot/Q8N1G2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015050
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055865
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