FTSJD2 (CMTR1) (NM_015050) Human Recombinant Protein

Product Specifications

Background

S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m (7) GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m (7) GpppRm (cap1) . Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human FtsJ methyltransferase domain containing 2 (FTSJD2)

Synonyms

FTSJD2; hMTr1; KIAA0082; MTr1

Gene ID

23070

UniProt

Q8N1G2

Accession Number mRNA

NM_015050

Chromosomal Location

6p21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

95.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.