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CD32A (FCGR2A) (NM_021642) Human Recombinant Protein

Product Specifications

Background

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

Overview

Recombinant protein of human Fc fragment of IgG, low affinity IIa, receptor (CD32) (FCGR2A), transcript variant 2

Synonyms

CD32; CD32A; CDw32; FCG2; FcGR; FCGR2; FCGR2A1; IGFR2

Gene ID

2212

UniProt

P12318

Accession Number mRNA

NM_021642

Chromosomal Location

1q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

Field of Research

Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

34.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FCGR2A

Species

Human

Protein ID

NP_067674

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2212

Uniprot URL

https://www.uniprot.org/uniprot/P12318

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021642

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_067674

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