M-CSF (CSF1) (NM_172212) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Overview

Recombinant protein of human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 4

Synonyms

CSF-1; MCSF

Gene ID

1435

UniProt

P09603, A0A024R0A1

Accession Number mRNA

NM_172212

Chromosomal Location

1p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytokine-cytokine receptor interaction, Hematopoietic cell lineage

Field of Research

Cytokine-cytokine receptor interaction, Hematopoietic cell lineage

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane

Molecular Weight

59.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.