TRF1 (TERF1) (NM_003218) Human Recombinant Protein
Product Specifications
Background
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]
Synonyms
HTRF1-AS; PIN2; t-TRF1; TRBF1; TRF; TRF1
Gene ID
7013
UniProt
P54274, P54274-2
Accession Number mRNA
NM_003218
Chromosomal Location
8q21.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
48.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TERF1
Species
Human
Protein ID
NP_003209
Overview
Recombinant protein of human telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7013
Uniprot URL
https://www.uniprot.org/uniprot/P54274
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003218
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003209
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