BIRC5 (NM_001168) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Synonyms
API4; EPR-1
Gene ID
332
UniProt
O15392, A0A0B4J1S3
Accession Number mRNA
NM_001168
Chromosomal Location
17q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Colorectal cancer, Pathways in cancer
Field of Research
Colorectal cancer, Pathways in cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency
Molecular Weight
16.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BIRC5
Species
Human
Protein ID
NP_001159
Overview
Recombinant protein of human baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/332
Uniprot URL
https://www.uniprot.org/uniprot/O15392
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001168
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001159
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