MAP4K5 (NM_198794) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
GCKR; KHS; KHS1; MAPKKKK5
Gene ID
11183
UniProt
Q9Y4K4, B3KWC4
Accession Number mRNA
NM_198794
Chromosomal Location
14q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
94.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MAP4K5
Species
Human
Protein ID
NP_942089
Overview
Recombinant protein of human mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11183
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y4K4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_198794
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_942089
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