Synaptotagmin 3 (SYT3) (NM_032298) Human Recombinant Protein

Product Specifications

Background

Ca (2+) sensor involved in Ca (2+) -dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain. Ca (2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human synaptotagmin III (SYT3)

Synonyms

SytIII

Gene ID

84258

UniProt

Q9BQG1, A0A024R4I9

Accession Number mRNA

NM_032298

Chromosomal Location

19q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein, Transmembrane

Molecular Weight

63.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.