THAP1 (NM_018105) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human THAP domain containing, apoptosis associated protein 1 (THAP1), transcript variant 1
Synonyms
DYT6
Gene ID
55145
UniProt
Q9NVV9
Accession Number mRNA
NM_018105
Chromosomal Location
8p11.21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
24.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
THAP1
Species
Human
Protein ID
NP_060575
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55145
Uniprot URL
https://www.uniprot.org/uniprot/Q9NVV9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018105
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060575
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