MTAP (NM_002451) Human Recombinant Protein
Product Specifications
Background
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]
Synonyms
BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP
Gene ID
4507
UniProt
Q13126, A0A384ME80
Accession Number mRNA
NM_002451
Chromosomal Location
9p21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cysteine and methionine metabolism, Metabolic pathways
Field of Research
Cysteine and methionine metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
31.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MTAP
Species
Human
Protein ID
NP_002442
Overview
Recombinant protein of human methylthioadenosine phosphorylase (MTAP)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4507
Uniprot URL
https://www.uniprot.org/uniprot/Q13126
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002451
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002442
Curated Selection
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