VPS45A (VPS45) (NM_007259) Human Recombinant Protein
Product Specifications
Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Overview
Recombinant protein of human vacuolar protein sorting 45 homolog (S. cerevisiae) (VPS45)
Synonyms
H1; H1VPS45; SCN5; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
Gene ID
11311
UniProt
Q9NRW7
Accession Number mRNA
NM_007259
Chromosomal Location
1q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
64.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VPS45
Species
Human
Protein ID
NP_009190
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11311
Uniprot URL
https://www.uniprot.org/uniprot/Q9NRW7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007259
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009190
Frequently Asked Questions
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