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PMP2 (NM_002677) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017]

Overview

Recombinant protein of human peripheral myelin protein 2 (PMP2)

Synonyms

CMT1G; FABP8; M-FABP; MP2; P2

Gene ID

5375

UniProt

P02689

Accession Number mRNA

NM_002677

Chromosomal Location

8q21.13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

14.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PMP2

Species

Human

Protein ID

NP_002668

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5375

Uniprot URL

https://www.uniprot.org/uniprot/P02689

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002677

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002668

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